Loïc Corbery was only six years old when director Agnès Varda cast him for her short feature Ulysse. In 1995, following a period with the Tremplin theatre company, the young native of Avignon moved to Paris to begin his training at the Cours Perimony which then led him to the Conservatoire national supérieur d'art dramatique in 1997. In 2000, his teacher Jacques Lassalle directed him in The Life of Galileo by Bertolt Brecht and later in The Dance School by Carlo Goldoni. They reunited again in 2006 to work on Loin de Corpus Christi by Christophe Pellet.

Loïc Corbery joined the Comédie-Française on the 17th of January 2005. He excelled as Dorante in Corneille’s Le Menteur directed by Jean-Louis Benoit. On the 1st of January 2010, he was appointed the 519th sociétaire of the Company. Besides contemporary authors, such as Ödön Von Horváth’s Figaro Gets a Divorce, Eduardo de Filipo’s La Grande Magie and Philippe Meyer’s singing shows, Loïc Corbery’s talents shine best in the classical repertoire. Jacques Lassalle thus cast him as Zorzello in Goldoni's Il Campiello, Lukas Hemleb as Clitandre in Molière's The Misanthrope, Oskaras Koršunovas as Petruchio in Shakespeare’s The Taming of the Shrew, Galin Stoev as Clindor in Corneille's L'Illusion comique, Andrés Lima as Fenton in Shakespeare’s Merry Wives of Windsor, Catherine Hiegel as Cléante in her staging of Molière’s The Miser (L’Avare). Denis Podalydès offered him the role of Christian in his staging of Edmond Rostand’s Cyrano de Bergerac and Yves Beaunesne that of Perdican in Alfred de Musset’s No Trifling with Love (On ne badine pas avec l’amour).
Clément Hervieu-Léger directed him in Molière’s The Misanthrope, and later on, in Le Petit-Maître corrigé by Marivaux. Anne Kessler cast him in Richard III staged at Radio France Culture to mark the 450th anniversary of Shakespeare’s birth before offering him the role of the Prince in Marivaux’s The Double Inconstancy (La Double inconstance). In 2016, Ivo van Hove cast him as Herbert Thallman in The Damned (Les Damnés), adapted from Visconti’s screenplay and premiered at The Festival d’Avignon. In 2018, he played in Shakespeare’s The Tempest as staged by Canadian Robert Carsen.

On film, Loïc Corbery most notably worked with Jim Jarmusch in Only Lovers Left Alive, with Lucas Belvaux in Not My Type and with Wim Wenders in Submergence